Responding to peer-review comments professionally is an important part of the publication process and can significantly influence how editors and reviewers view a revised manuscript. Authors should approach reviewer feedback with a clear, respectful, and evidence-based response, addressing each comment individually and explaining precisely what has been changed. When a suggested revision is appropriate, the manuscript should be updated accordingly; when authors disagree with a comment, they should provide a concise scientific rationale supported by relevant evidence rather than responding defensively. A well-organized response letter, with reviewers’ comments clearly separated from the authors’ responses and revisions identified by page or line number, helps demonstrate that the feedback has been carefully considered and that the revised manuscript is stronger, clearer, and more rigorous.

